An Ex Vivo 3 Dimensional Organotypic Culture Model: A First Attempt to Stimulate Endochondral Ossification of the Growth Plate in Vitro
Eingereicht von: Sriveena Srinivasaiah, MSc
Firma/Universität: Medical University of Graz – University Clinics for Orthopedics and Traumatology
Kooperationspartner: Helmholtz-Zentrum Geesthacht GmbH; Mayo clinic
- The model can benefit the scientific and pharmaceutical community by providing an ultimate
bone template that can be subjected to various testing’s.
- This is a great model to investigate bone trauma and lesions caused in young children.
- Most importantly from the ethical standpoint it reduces the use of animals and promotes
alternative testing strategies.
- Since it provides a scope to discover novel biomarkers, the knowledge could be substantially
expanded to preclinical investigations and therapeutical interventions.