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Scientist – Immunology and In Vitro Models


Stellenangebot, Job, Scientist – Immunology and In Vitro Models, x4Pharmaceuticals



Scientist – Immunology and In Vitro Models

About X4 Pharmaceuticals

Our commitment is to find solutions for patients. Every day, we strive to advance our pipeline of innovative medicines to treat rare diseases. Our first-in-class, oral, small molecule therapeutics are antagonists of chemokine receptor CXCR4, which have the potential to treat a broad range of rare diseases, including primary immunodeficiencies (PIs) and cancer.

X4 Pharmaceuticals, Inc. was founded and is led by a team with deep product development and commercialization expertise, including several former members of the Genzyme leadership team and has its headquarter located in Cambridge, Massachusetts.

X4’s research and development facility in Vienna, Austria, X4 Pharmaceuticals (Austria) GmbH is located on Campus Vienna Biocenter (Helmut-Qualtinger-Gasse 2, 1030 Vienna) and is run by a team of highly motivated scientists and technicians who are dedicated to build a Center of Research Excellence in the field of small molecule therapeutics. X4 Pharmaceuticals (Austria) GmbH is currently offering a full-time employment contract for a Scientist – Immunology and In Vitro Models.

Summary of the position:

As part of our team, the Scientist – Immunology and In Vitro Models will

• Perform research in the field of rare primary immunodeficiencies and cancer
• Be responsible for the planning, coordination, documentation, and execution of laboratory experiments in the areas of immunology and cell biology
• Establish novel cell based in-vitro and ex-vivo immune models, using (primary) human immune cells, for evaluation and mode of action studies of new therapeutics
• Present data at internal and external meetings and extend knowledge by attending scientific conferences
• Support the team in writing reports and manuscripts

Qualifications and skills:

• PhD or Post Doc in immunology, molecular biology or a related discipline
• Experience in the development of bioassays
• Strong experience in mammalian cell culture including isolation and propagation of human and mouse immune cells
• Hands-on experience in human and murine cellular immunology methods using primary and expanded immune cells (e.g. T cells, B cells, myeloid cells, co-culture assays and other primary cell assays)
• Experience in analysis of proteins and cytokines by single and multiplex platforms
• Experience in multi-color flow cytometry and fluorescence microscopy
• Experience with DNA cloning and gene manipulation methods
• Prior research experience in immunodeficiencies and or GPCRs is a plus
• Clear ambition to learn about and implement new technologies and open to new challenges
• Proficiency in data analysis and presentation tools
• Proven ability to troubleshoot technical and scientific issues
• Excellent oral and written communication skills in English
• Collaborative team player attitude

We are offering:

• A strong, dedicated and multinational team of scientists and technicians
• An open, transparent and collegial working environment
• Opportunities for your personal development and to play a key role in a growing international research center
In accordance with Austrian employment law, the minimum monthly gross salary for the position is EUR 3.348,82 which we are willing to adjust according to your qualifications, skills and expertise.

Please send your resume and cover letter in English to